Indication:
Olmesartan Medoxomil
Angiotensin Receptor Blocker (Cardiovascular Preparations)
Preparation:
OlmecarTM 20 tablet: Each box contains 30 tablets in blister pack. OlmecarTM 40 tablet: Each box contains 30 tablets in blister pack.
DOSAGE & ADMINISTRATION
Dosage must be individualized. The usual recommended starting dose of
Olmesartan is 20 mg once daily when used as monotherapy in patients who are
not volume-contracted. For patients requiring further reduction in blood pressure
after 2 weeks of therapy, the dose of Olmesartan may be increased to 40 mg.
Doses above 40 mg do not appear to have greater effect. Twice-daily dosing
offers no advantage over the same total dose given once daily.
No initial dosage adjustment is recommended for elderly patients, for patients
with moderate to marked renal impairment (creatinine clearance < 40 ml/min) or
with moderate to marked hepatic dysfunction. For patients with possible
depletion of intravascular volume (e.g., patients treated with diuretics,
particularly those with impaired renal function), Olmesartan should be initiated
under close medical supervision and consideration should be given to use of a
lower starting dose. Olmesartan may be administered with or without food.
